Publications

2018

  • C.-M. Lee, S.J. Cho, W.K. Cho, J.W. Park, A.M. Choi, I.O. Rosas, M. Zheng, G. Peltz, C.G. Lee, J.A. Elias. Laminin alpha1 is a genetic modifier of TGF-b1-stimulated pulmonary fibrosis. JCI Insight pii: 99574. doi: 10.1172/jci.insight.99574, 2018.
  • G. Peltz and T.C. Sudhof. The Neurobiology of Opioid Addiction and the Potential for Prevention Strategies JAMA 319:2071, 2018.
  • G. Peltz. A Flawed Design Produces Flawed Results. Journal of Addiction Medicine 12:252, 2018

2017

  • Y. Guan, D. Xu, P.M. Garfin, U. Ehmer, M. Hurwitz, G. Enns, S. Michie, M. Wu, M. Zheng, T. Nishimura, J. Sage and G. Peltz. Human Hepatic Organoids for the Analysis of Human Genetic Diseases. JCI Insight 2: pii: 94954, 2017.
  • Angela Rogers, Kevin Contrepois, Manhong Wu, Ming Zheng, Gary Peltz, Lorraine Ware, and Michael Matthay. Profiling of ARDS Pulmonary Edema Fluid Identifies a Metabolically Distinct Subset. American Journal of Physiology – Lung Cellular and Molecular Physiology 312:L703-9, 2017.
  • Meng How Tan, Q. Li, R. Shanmugam, R. Piskol, J. Kohler, A.N. Young, K.I. Liu, R. Zhang, G. R.K. Ariyoshi, A. Gupte, L.P. Keegan, C.X. George, Ni Huang, E.A. Pollina, D. Leeman, A. Rustighi, Y.P.S. Goh, The GTEx Consortium, A. Chawla, G. Del Sal, G.Peltz, A. Brunet, D.F. Conrad, C.E. Samuel, M.A.O. Connell, C.R. Walkley, K. Nishikura and Jin Billy Li. Dynamic landscape and regulation of RNA editing in mammals. Nature 550:249-54, 2017.
  • M. Erlendson, N. D’Arcy, E. Encisco, J. Yu, L. Rincon-Cruz, Gary Peltz, J.D. Clark, L. Chu. Pretreatment with Palonosetron and Hydroxyzine Reduces Signs but not Symptoms of Experimentally-Induced Acute Opioid Withdrawal in Humans: A Double-Blinded, Randomized, Placebo-Controlled Crossover Study. Am J Drug Alcohol Abuse 43:78-86, 2017.

2016

  • Yuan Guan, Dan Xu, and Gary Peltz. Treating Liver Fibrosis: (Re)programmed to succeed. Cell Stem Cell 18: 683-4 (2016).
  • R. Donaldson; Y. Sun; D. Liang; M. Zheng; P. Sahbaie; D. Dill; G. Peltz; K. Buck; D. Clark. The multiple PDZ domain protein Mpdz/MUPP1 regulates opioid tolerance and opioid-induced hyperalgesia. BMC Genomics 17:313 (2016).
  • H. Zhang, M. Zheng, M. Wu, D. Xu, T. Nishimura, Yuki Nishimura, R. Giffard, X. Xiong, L. Jun Xu, J. D. Clark, P. Sahbaie, D.L. Dill, and G Peltz. A Pharmacogenetic Discovery: Cystamine Protects against Haloperidol-Induced Toxicity and Ischemic Brain Injury. Genetics 203: 599-609 (2016).
  • Smith J, Suresh S, Schlecht U, Wu M, Wagih O, Peltz G, Davis RW, Steinmetz L, Part L, St.Onge RP. CRISPR interference screens in yeast identify chemical-genetic interactions and new rules for guide RNA design. Genome Biology 17:45 (2016).
  • D. Xu, G. Peltz. Can Humanized Mice Predict Drug Behavior in Humans? Annual Review of Pharmacology and Toxicology 56: 323-38 (2016).

2015

  • G. Peltz and K.J.S. Anand. Long acting opioids for treating Neonatal Abstinence Syndrome: A high price for a short stay?  JAMA 314: 2023-2024 (2015).
  • D. Xu, S.A. Michie, M. Zheng, S. Takeda, M. Wu and G. Peltz. Humanized TK-NOG mice can be used to identify drugs that cause animal-specific hepatotoxicity: a case study with furosemide. J. Pharmacology and Exp. Therapeutics 354:73-8 (2015).
  • Xu, M. Wu, S. Nishimura, T. Nishimura, S.A. Michie, M. Zheng, Z. Yang, A.J. Yates, J.S. Day, K.M. Hillgren, S. Takedai Takeda, Y. Guan, Y.Y. Guo, and G. Peltz. Chimeric TK-NOG Mice: A Predictive Model for Cholestatic Human Liver Toxicity. J. Pharmacology and Exp. Therapeutics 352:274-80 (2015).
  • Zheng M, Zhang H, Dill DL, Clark JD, Tu S, Yablonovitch AL, Tan MH, Zhang R, Rujescu D, Wu M, Tessarollo L, Vieira W, Gottesman MM, Deng S, Eberlin LS, Zare RN, Billard J-M, Gillet J-P, L JB, Peltz G The Role of Abcb5 Alleles in Susceptibility to Haloperidol-Induced Toxicity in Mice and Humans. PLoS Medicine 12:e1001782 (2015).
  • D. Drover, M. Elkomy, P. Sultan, B. Carvalho, G. Peltz, M. Wu, C. Clavijo, and J. Galinkin. Ondansetron Pharmacokinetics in Pregnant Women and Neonates: Towards a New Treatment for Neonatal Abstinence Syndrome. Clinical Pharmacology and Therapeutics 97:167-76 (2015).

2014

  • D-Y. Liang, M. Zheng, Y. Sun, P. Sahbaie, S.A. Low, G. Peltz, G. Scherrer, C. Flores and J. D. Clark. The Netrin-1 Receptor DCC is a Regulator of Maladaptive Responses to Chronic Morphine Administration. BMC Genomics (2014) 15:345.
  • Dan Xu, Toshihiko Nishimura, Sachiko Nishimura, Haili Zhang, Ming Zheng, Ying-Ying Guo, Marylin Masek, Sara A. Michie, Jeffrey Glenn, and Gary Peltz. Fialuridine Induces Acute Liver Failure in Chimeric TK-NOG Mice: A Model for Detecting Hepatic Drug Toxicity Prior to Human Testing. PLOS Medicine (2014) 11: e1001628  PMID: 24736310.
  • Dan Xu, Toshihiko Nishimura, Ming Zheng, Manhong Wu, Hua Su, Noboru Sato, Gordon Lee, Sara Michie, Jeffrey Glenn, and Gary Peltz. Enabling Autologous Human Liver Regeneration With Differentiated Adipocyte Stem Cells (2014) Cell Transplantation 23:1573-84.

2013

  • J.J. Gallagher, M. Tajerian, T. Guo, X.Y. Shi, W. Li, M. Zheng, G. Peltz, W.S. Kingery and D.J. Clark. Acute and Chronic Phases of Complex Regional Pain Syndrome in Mice are Accompanied by Distinct Transcriptional Changes in the Spinal Cord. (2013) Molecular Pain 9:40.
  • Park W, Wu M, Bowen R, Zheng M, Fitch WL, et al. Metabolomic Markers Differentiate Mucinous and Non-Mucinous Pancreatic Cysts. (2013) Gastrointestinal Endoscopy 78:295-302. PMID: 23566642.
  • Manhong Wu, William L. Fitch, Ming Zheng, Robert E. Merritt, Joseph B. Shrager, Weiruo Zhang, David L. Dill, Gary Peltz and Chuong D. Hoang. Liquid chromatography/mass spectrometry methods for measuring dipeptide abundance in non-small-cell lung cancer (2013) Rapid Communications in Mass Spectroscopy 27:2091-98. PMID: 23943330.
  • Peltz G Can ‘Humanized’ Mice Improve Drug Development in the 21st Century? (2013) Trends in Pharmacological Sciences 34:255-60. PMID: 23602782.
  • Y. Hu, M. Wu, T. Nishimura, M. Zheng, G. Peltz. Human pharmacogenetic analysis in chimeric mice with “humanized livers”. Pharmacogenetics and Genomics (2013) 23(2): 78-83. PMID: 23241944.
  • Nishimura, Y. Hu, M. Wu, E. Pham, H. Suemizu, M. Elazar, M. Liu, R. Idilman, C. Yurdaydin, P. Angus, C. Stedman, B. Murphy, J. Glenn, M. Nakamura, T. Nomura, Y. Chen, M. Zheng, W.L. Fitch, and G Peltz. Using Chimeric Mice with Humanized Livers to Predict Human Drug Metabolism and a Drug-Drug Interaction. J. Pharmacology and Exp. Therapeutics (2013) 344: 388-98. PMID: 23143674.

2012

  • M. Wu, P. Sahbaie, M. Zheng, R. Lobato, D. Boison, J. D. Clark, and G. Peltz. Opiate-induced Changes in Brain Adenosine Levels and Narcotic Drug Responses (2012) Neuroscience 228: 235-42. PMID:23098802
  • Wu, M. Zheng, W. Zhang, S. Suresh, U. Schlecht, W.L. Fitch, S. Aronova, S. Baumann, Davis, R. St.Onge, D.L. Dill, G. Peltz. Identification of Drug Targets by Chemogenomic and Metabolomic Profiling in Yeast. Pharmacogenetics and Genomics (2012) 22:877-86. PMID: 23076370
  • Ming Zheng, David Dill, J. David Clark, and Gary Peltz. Computational Genetic Discoveries that could Improve Perioperative Medicine. Current Opinion in Anesthesiology (2012) 25(4):428-33.
  • H-H. Liu, Y. Hu, M. Zheng, M.M. Suhoski, E.G. Engleman, D. Dill, M. Hudnall, J. Wang, R. Spolski, W.J. Leonard and G. Peltz. Cd14 SNPs Regulate the Innate Immune Response. Molecular Immunology (2012) 51:112-127.
  • Sorge, R. E., T. Trang, R. Dorfman, S. B. Smith, S. Beggs, J. Ritchie, J.-S. Austin, D. V. Zaykin, H. V. Meulen, M. Costigan, T. A. Herbert, M. Yarkoni-Abitbul, D. Tichauer, J. Livneh, E. Gershon, M. Zheng, K. Tan, S. L. John, G. D. Slade, J. Jordan, C. J. Woolf, G. Peltz, W. Maixner, L. Diatchenko, Z. Seltzer, M. W. Salter, and J. S. Mogil. Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity (2012) Nature Medicine 18:595-600.
  • M. Zheng, M, Dill D., Peltz, G. A Better Prognosis for Genetic Association Studies in Mice Trends in Genetics (2012) 28 (2):62-69.

2011

  • Peltz G, Zaas AK, Zheng M, Solis NV, Zhang MX, Liu H-H, Hu Y, Boxx GM, Phan QT, Dill D, and S. Filler. Next-Generation Computational Genetic Analysis: Multiple Complement Alleles Control Survival After Candida Albicans Infection and Immunity (2011): 79: 4472-79. PMID: 21875959.
  • A.C.M. Boon, D. Finkelstein, G. Liao, M. Zheng, J. Allard, K. Klump, R. Webster, G. Peltz, R.J. Webby. H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load. (2011) mBio 2(5). pii: e00171-11. PMID: 21896679.
  • G. Peltz. Immunomodulation in perioperative medicine. Pain Management In press, 2011.
  • Hasegawa M, Kawai K, Mitsui T, Taniguchi K, Monnai M, Wakui M, Ito M, Suematsu M, Peltz G, Nakamura M et al: The reconstituted ‘humanized Liver’ in TK-NOG mice is mature and functional. Biochem Biophys Res Commun 2011, 405(3):405-410.
  • M. Zheng, G. Peltz.  Genetic discovery: The prescription for chronic pain. Genomic Medicine 2:82-84, 2011.
  • X. Zhang, H-H. Liu, P. Weller, M. Zheng, J. Wang, G. Liao, M. Monshouwer and G. Peltz. In Silico and In Vitro Pharmacogenetics: Aldehyde Oxidase Rapidly Metabolizes a P38 Kinase Inhibitor.  The Pharmacogenetics Journal 11:15-24, 2011.

2010

  • J.S. Tregoning, Y. Yamaguchi, B. Wang, D. Mihm, J.A. Harker, E.S.C. Bushell, M. Zheng, G. Liao, G. Peltz and P.J.M. Openshaw. Genetic Susceptibility to the Delayed Sequelae of RSV Infection is MHC-Dependent, but Modified by Other Genetic Loci. J. Immunol. 185:5384-91,2010.
  • Zheng, P. Ravindran, J. Wang, R.H. Epstein, D.P. Chen, A.J. Butte, and G. Peltz. An Optimistic Prognosis For the Clinical Utility of Laboratory Test Data. Anesthesia & Analgesia 111:1026-1035, 2010.
  • Y. Hu, D. Liang, X. Li, H-H. Liu, Xun Zhang, M. Zheng, D. Dill, X. Shi, Y. Qiao, D. Yeomans, B. Carvalho, M.S. Angst, J.D. Clark, G. Peltz. The Role of IL-1 in Wound Biology Part II: In vivo and Human Translational Studies. Anesthesia & Analgesia 111(6):1534-42, 2010.
  • Y. Hu, D. Liang, X. Li, H-H. Liu, Xun Zhang, M. Zheng, D. Dill, X. Shi, Y. Qiao, D. Yeomans, B. Carvalho, M.S. Angst, J.D. Clark, G. Peltz. The Role of IL-1 in Wound Biology Part I: Murine in Silico and In vitro Experimental Analysis. Anesthesia & Analgesia 111: 1525-33, 2010.
  • X. Li, P. Sahbaie, M. Zheng, J. Ritchie, G. Peltz, J.S. Mogil and J. D. Clark. Expression Genetics Identifies Spinal Mechanisms Supporting Formalin Late Phase Behaviors (2010).  Molecular Pain, 6:11, 2010.
  • H.-H. Liu, P. Lu, Y. Guo, E. Farrell, X. Zhang, M. Zheng, B. Bosano, Z. Zhang, J. Allard, G. Liao, S. Fu, J. Chen, K. Dolim, A. Kuroda, J. Usuka, J. Cheng, W. Tao, K. Welch., Y. Liu, J. Pease, S.A. de Keczer, M. Masjedizadeh, J.-S. Hu, P. Weller, T. Garrow, and G. Peltz. Bhmt2 is a Genetic Susceptibility Factor For Acetaminophen-Induced Liver Toxicity (2010). Genome Research, 20:28-35.

2010

  • J.S. Tregoning, Y. Yamaguchi, B. Wang, D. Mihm, J.A. Harker, E.S.C. Bushell, M. Zheng, G. Liao, G. Peltz and P.J.M. Openshaw. Genetic Susceptibility to the Delayed Sequelae of RSV Infection is MHC-Dependent, but Modified by Other Genetic Loci. J. Immunol. 185:5384-91,2010.
  • Zheng, P. Ravindran, J. Wang, R.H. Epstein, D.P. Chen, A.J. Butte, and G. Peltz. An Optimistic Prognosis For the Clinical Utility of Laboratory Test Data. Anesthesia & Analgesia 111:1026-1035, 2010.
  • Y. Hu, D. Liang, X. Li, H-H. Liu, Xun Zhang, M. Zheng, D. Dill, X. Shi, Y. Qiao, D. Yeomans, B. Carvalho, M.S. Angst, J.D. Clark, G. Peltz. The Role of IL-1 in Wound Biology Part II: In vivo and Human Translational Studies. Anesthesia & Analgesia 111(6):1534-42, 2010.
  • Y. Hu, D. Liang, X. Li, H-H. Liu, Xun Zhang, M. Zheng, D. Dill, X. Shi, Y. Qiao, D. Yeomans, B. Carvalho, M.S. Angst, J.D. Clark, G. Peltz. The Role of IL-1 in Wound Biology Part I: Murine in Silico and In vitro Experimental Analysis. Anesthesia & Analgesia 111: 1525-33, 2010.
  • X. Li, P. Sahbaie, M. Zheng, J. Ritchie, G. Peltz, J.S. Mogil and J. D. Clark. Expression Genetics Identifies Spinal Mechanisms Supporting Formalin Late Phase Behaviors (2010).  Molecular Pain, 6:11, 2010.
  • H.-H. Liu, P. Lu, Y. Guo, E. Farrell, X. Zhang, M. Zheng, B. Bosano, Z. Zhang, J. Allard, G. Liao, S. Fu, J. Chen, K. Dolim, A. Kuroda, J. Usuka, J. Cheng, W. Tao, K. Welch., Y. Liu, J. Pease, S.A. de Keczer, M. Masjedizadeh, J.-S. Hu, P. Weller, T. Garrow, and G. Peltz. Bhmt2 is a Genetic Susceptibility Factor For Acetaminophen-Induced Liver Toxicity (2010). Genome Research, 20:28-35.

2009

  • Zheng, M., Shafer, S.S., Liao, G., Liu, H.-H., and Peltz, G. Computational Genetic Mapping in Mice: ‘The Ship has Sailed’ (2009). Science Translational Medicine, 1:3ps4.
  • M.L. LaCroix-Fralish, S.B. Smith, G. Mo, S.G. Sotocinal, J. Ritchie, J.-S. Austin, K. Melmed, T.H. Lee, D. Romanovsky, G. Liao, M.A. Behlke, D. J. Clark, G. Peltz, P. Séguéla, M. Dobretsov and J.S. Mogil. Genetic Variation within the b3 Subunit (Atp1b3) of the Na+,K+-ATPase Alters Inflammatory Pain Sensitivity (2009). Pain, 144:294-302.
  • L. Chu, D-Y. Liang, X. Li, P. Sahbaie, N. D’Arcy, G. Liao, G. Peltz, and J. D. Clark.  From Mouse to Man: The 5HT3 Receptor Modulates Physical Dependence on Narcotic Drugs (2009).  Pharmacogenetics and Genomics. 19: 193-205.

2008

  • H. Suemizu, M. Hasegawa, K. Kawai, K. Taniguchi, M. Monnai, M. Wakui, M. Suematsu, M. Ito, G. Peltz and M. Nakamura (2008).  Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice.  Biochemical Biophysical Research Communications.  377: 248-52.
  • G.J. Tranah, B.C. Taylor, Li-Y. Liu, J.M. Zmuda, J.A. Cauley, Kristine E. Ensrud, T.A. Hillier, M.C. Hochberg, J. Li, Brian Rhees, H. Erlich, M.D. Sternlicht, G. Peltz, and S. R. Cummings, for the SOF Research Group (2008).  A candidate gene study of fracture risk and bone mineral density: results from the Study of Osteoporotic Fractures. Calcified Tissue International.  83:155-66.
  • Moffett, S. P., Oakley, J. I., Cauley, J. A., Lui, L. Y., Ensrud, K. E., Taylor, B. C., Hillier, T. A., Hochberg, M. C., Li, J., Cayabyab, S., Lee, J. M., Peltz, G., Cummings, S. R., Zmuda, J. M. Osteoprotegerin Lys3Asn Polymorphism and the Risk of Fracture in Older Women. J. Clinical Endocrinology and Metabolism.  93:2002-8, 2008.
  • Aimee Zaas, Guochun Liao, Jason Chien, Jonathan Usuka, Clarice Weinberg, David Shore, Steven Giles, Kieren Marr, Lauranell Burch, Lalith Perara, John Perfect, Gary Peltz, David Schwartz. Plasminogen Alleles Influence Susceptibility to Invasive Aspergillosis (2008).  PLoS Genetics. 4: e1000101, 2008.
  • E.Y. Kim, J.T. Battaile, A.C. Patel, E. Agapov, M.H. Grayson, Y. You, Y. Alevy, J. Tucker, S. Swanson, J.W. Tyner, J.D. Morton, M.Castro, G.A. Patterson, J.C. Woods, G. Reto, A. Schwendener, J.D. Allard, G. Peltz, and M.J. Holtzman. Persistent activation of an innate NKT cell-macrophage immune axis translates respiratory viral infection into chronic inflammatory lung disease. Nature Medicine, 14:633-40, 2008.
  • S.B. Smith, C.L. Marker, C. Perry, S.G. Sotocinal, J.-S. Austin, K. Melmed, G. Liao, G. Peltz, D.J. Clark, K. Wickman, and J.S. Mogil. Quantitative Trait Locus and Computational Mapping Identifies Kcnj9 (GIRK3) as a Candidate Gene Affecting Analgesia from Multiple Drug Classes, Pharmacogenetics and Genomics,\ 18:231-41, 2008.
  • . G. Liao, J.D. Clark, G. Peltz.  A Genomic ‘Roadmap’ to ‘Better’ Drugs.  Drug Metabolism Reviews, 40:225-39, 2008.
  • Sabsovitch, I., Clark, J.D., Liao, G., Peltz, G., Lindsey, D.P., Jacobs, J.R., Yao, W., Guo, T-Z., W.S. Kingery.  Bone Microstructure and its Associated Genetic Variability in 12 Inbred Mouse Strains: µCT Study and In Silico Genome Scan. Bone 42:439-51, 2008.

2007

  • Yingying Guo, Erin Farrell, Peng Lu, Paul Weller, Jianmei Wang, Guochun Liao, Zhaomei Zhang, Steven Hu, John Allard, Steve Shafer, Jonathan Usuka, and Gary Peltz.  In silico and In vitro Computational Pharmacogenetics in mice.  Proceedings of the National Academy of Science 104:17735-40, 2007.
  • Zheng, M., Lu, P., Liu, Y., Pease, J., Usuka, J., Peltz, G., and Guochun Liao.  An Automated Method for Analysis of 2-Dimensional 1H-13C NMR Spectra (2007). Bioinformatics 21:2926-2933.
  • Adachi, K., Mirzadeh, Z., Sakaguchi, M., Yamashita. T., Nikolcheva, T., Peltz, G., Gong, L., Gotoh, Y., Alvarez-Buylla, A., Kawase,  T., Okano, H., and Sawamoto, K.  b-catenin Signaling Promotes Proliferation of Progenitor Cells in the Adult Mouse Subventricular Zone.  Stem Cells 25: 2827-36, 2007.
  • Moffett, S.P., Zmuda, J.M., Cauley J.A., Ensrud K.E., Hillier T.A., Hochberg M.C., Li J., Cayabyab S., Lee J. M, Peltz G., Cummings S.R. Association of the VDR translation start site polymorphism and fracture risk in older women. Journal of Bone and Mineral Research 22: 730-6, 2007.
  • Cascio,  M., Xing, Y., Gong, D., Popovich, J., Eger, E., Saunak Sen, Peltz, G., Sonner, J.M.  Mouse chromosome 7 harbors a quantitative trait locus for isoflurane minimum alveolar concentration.  Anesthesia and Analgesia 105: 381-385, 2007.
  • A.C. Blackburn, Hill, L.Z., Roberts A., Wang, J., Aud, D., Jung, J., Nikolcheva, T., Allard, J., Otis, C.N., Cao, J., Ricketts S.J.R., Naber, S.P., Dickinson E., Peltz, G.,  and D.J. Jerry. Low DMBT1 Expression Correlates with Breast Cancer Susceptibility in Mice and Humans. Am. J. Pathology 170:2030-2041, 2007.
  • J.G. Koch, X. Gu, Y. Han, A. El-Naggar, D. Medina, D. J. Jerry, A. C. Blackburn, G. Peltz, C. Amos, and G. Lozano.  Mammary tumor modifiers in BALB/cJ mice heterozygous for p53.  Mammalian Genome 18:300-309, 2007.

2006

  • D-Y. Liang, G. Liao, G. Lighthall, G. Peltz and J. D. Clark (2006). Genetic Variants of the P-Glycoprotein Gene Abcb1b Modulate Opioid-Induced Hyperalgesia, Tolerance and Dependence. Pharmacogenetics and Genomics 16: 825-835, 2006.
  • Guo, Y., Weller, P., Farrell, E., Cheung, P.,  Fitch, B., Clark, D., Wu,S.-Y., Wang, J., Liao, G., Zhang, Z., Allard, J., Cheng, J., Nguyen, A., Jiang, S., Shafer, S., Usuka, J., Masjedizadeh, M. and G. Peltz.  In Silico Pharmacogenetics: Warfarin Metabolism. Nature Biotechnology 24: 531-536, 2006.
  • Y. Guo, P. Weller, J. Allard, J. Usuka, M. Masjedizadeh, S-Y. Wu, B. Fitch, D. Clark, J.D. Clark, S. Shafer, J. Wang, G. Liao and G. Peltz.  Understanding Our Drugs and Our Diseases.  Proceedings of the American Thoracic Society  3: 409-412, 2006.
  • D.Y. Liang, T. Guo, G. Liao, W. Kingery, G. Peltz and J.D. Clark.  Chronic Pain and Genetic Background Interact and Influence Opioid Analgesia, Tolerance and Physical Dependence.  Pain 121: 232-240, 2006.
  • A.C. Patel J.D. Morton, E.Y. Kim, Y. Alevy, S. Swanson, J. Tucker, G. Huang, E. Agapov, T.E. Phillips, J.D. Allard, K. Dabbagh, G. Peltz, and M.J. Holtzman.  Genetic segregation of airway disease traits despite redundancy of chloride channel calcium-activated (CLCA) family members.  Physiological Genomics  25: 502-513, 2006.
  • Liang, D., Liao, G., Wang, J., Usuka, J., Gou, J., Peltz, G. and Clark, D.J.  Genetic Analysis of Opioid-Induced Hyperalgesia in Mice. Anesthesiology 104: 1054-1062, 2006.

2005

  •  Guo, Y.; Shafer, S.: Usuka, J.; Peltz, G. The Pharmacogenomic Road Ahead.  Pharmacogenetics.  6:857-864, 2005.
  • Moffett, S.P.; Zmuda, J.M.;  Oakley, J.M.; Beck, T.J.; Cauley, J.A.,Stone,K.L., Lui,L.Y.;Ensrud, K.E., Hillier,T.A., Hochberg, M.A.; Morin,P.; Peltz, G; Greene,D.; Cummings, S.R.Tumor Necrosis Factor Alpha Polymorphism, Bone Strength Phenotypes, and the Risk of Fracture in Older Women.  J. Clin. End. Metab. 90: 3492-3497, 2005.
  • Usuka, J.; Peltz, G. From Mouse Genetics to Human Therapeutics.  Current Opinion in Drug Discovery and Development 8: 253, 2005.
  • Wang, J.; Liao,G.; Usuka, J.; Peltz, G.  Computational Genetics: From Mouse to Man? Trends in Genetics 21: 526-532, 2005.
  • Wang,J.; Liao,G.; Chang,J.; Nguyen,A.; Guo,J.; Chou,S.; Hu,S.; Bach,C.; Allard,J.; Shafer,S.; Puech,A.; McPherson,J.D.; Foernzler,D.; Peltz,G.; Usuka,J.  Haplotypic Structure of the Mouse Genome.  Chapter 4 in Computational Genetics: New Tools for Disease Biology  G. Peltz, editor. Trenton: Humana Press, 2005.
  • Wang, J., Peltz, G. Haplotype-Based Computationa Genetic Analysis in Mice. Chapter 3 in Computational Genetics: New Tools for Disease Biology.  G. Peltz, Editor. Trenton: Humana Press, 2005.
  • Peltz, G.  Computational Biology Are We There Yet? Chapter 1 in Computational Genetics: New Tools for Disease Biology.  G. Peltz, Editor. Trenton: Humana Press, 2005.

2004

  • Wang,J.; Liao,G.; Chang,J.; Nguyen,A.; Guo,J.; Chou,S.; Hu,S.; Allard,J.; Shafer,S.; Puech,A.; McPherson,J.D.; Foernzler,D.; Peltz,G.; Usuka,J.  In Silico Genetics: Identification of A Novel Functional Element Regulating H2-Ea Gene Expression.  Science 306:690-96, 2004.
  • Savov, J.D., Whitehead,G.S., Foster,W.M.,Wang,J.,Liao,G., Usuka,J., Peltz,G., Schwartz,D.A.  O3-Induced Acute Pulmonary Injury in Inbred Mouse Strains.  Am. J. Resp. Cell Mol. Biol. 31: 69-77, 2004.
  • Klein,R.F.; Alard,J.; Avnur,Z.; Nikolcheva,T.; Rotstein,D.; Carlos,A.S.; Shea,M.; Waters,R.V.; Belknap,J.K.; Peltz,G.; Orwoll,E.S.  Regulation of Bone Mass in Mice by the Lipoxygenase Gene Alox15Science 303:229-232, 2004.

2003 and Earlier

  • Noble, J.A., White, Amy, M., Lazzeroni, L.C., Valdes, A.M., Mirel, D.B., Reynolds, R., Grupe, A., Aud, D., Peltz, G., Erlich, H.A. (2003).  A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. Diabetes 52: 1579-82.
  • Rozzo,S; Allard,J.D;Choubey,D; Vyse,T.;Izui,S.;Peltz,G.;Kotzin,B.L.  Evidence for an interferon-inducible gene, ifi202, in the susceptibility to Systemic Lupus.  Immunity  15:1,2001.
  • Grupe,A.; Germer,S.; Usuka,J; Aud,D.; Belknap,J.K.; Klein,R.F.; Ahluwalia,M.K.; Higuchi,R.; Peltz,G. In Silico Mapping of Complex Disease-Related Traits in Mice. Science  292:1915, 2001.
  • Karp,C.L.; Grupe,A.; Schadt,E.; Ewart,S.; Keane-Moore,M.; Cuomo,P.J; Kohl,J.; Wahl,L.; Kuperman,D.; Germer,S.; Aud,D.; Peltz,G.; Wills-Karp,M. Identification of Complement Factor 5 (C5) as a Susceptibility Factor for Experimental Allergic Asthma.  Nature Immunology 1:221, 2000.
  • Ewert,S.; Kuperman,D.; Schadt,E.; Tankersley,C.; Grupe,A.; Shubitowski,D.M.; Peltz,G.; Wills-Karp,M. Quantitative Trait Loci Controlling Allergen-Induced Airway Hyperresponsiveness in Inbred Mice. Am J Respir Cell Mol Biol.  23: 537-45, 2000.
  • Guler ML, Gorham JD, Dietrich WF, Steen RG, Parvin C, Fenoglio D, Grupe A, Peltz G, Murphy KM. Loci influencing development of Th responses. Identification from in vitro analysis.  Microbes Infect. 1:79-88,1999.
  • Ranganath,S.; Ouyang,W.; Bhattarcharya,D.; Sha,W.C.; Grupe,A.; Peltz,G.; Murphy,K.M. GATA-3-dependent enhancer activity in IL-4 gene regulation.  Journal of Immunology 161:3822-26,1998.
  • Guler ML. Gorham JD. Dietrich WF. Murphy TL. Steen RG. Parvin CA. Fenoglio D. Grupe A. Peltz G. Murphy KM. (1999) Tpm1, a locus controlling IL-12 responsiveness, acts by a cell-autonomous mechanism. Journal of Immunology 162, 1339-1347.
  • Ranganath S. Ouyang WJ. Bhattarcharya D. Sha WC. Grupe A. Peltz G. Murphy KM (1998) Gata-3-dependent enhancer activity in IL-4 gene regulation. Journal of Immunology 161, 3822-3826.
  • Peltz,G.  Transcription factors in immune-mediated disease.  Current Opin. Biotech. 8:467-73, 1997.
  • Turcovski-Corrales,S.M., Fenton, R.G., Peltz., G, Taub, D.D. CD28:B7 interactions promote T cell adhesion. European Journal of Immunology 25:3087-93,1995.
  • Lahesmaa,R., Allsup,A., Soderberg, C., Jackman, J., Findell, P., and G. Peltz.  Modulation of the grb2-associated protein complex in human CD4+ Tcells by receptor activation. J.Immunol. 155:3815-22, 1995.
  • Shanafelt, M-C., Yssel, H.,  Soderberg, C., Steinman, L., Adelman, D., Peltz, G., and R. Lahesmaa.  CD45 isoforms on human T cell subsets.  J. Allergy Clin. Immunol. 98:433-40, 1996.
  • Lahesmaa, R., Shanafelt, M.C., Allsup, A., Soderberg, C., Anzola, J., Freitas, V., Turck, C., Steinman, L., Peltz, G.  Preferential usage of T cell antigen receptor V region gene segment V beta 5.1 by Borrelia burgdorferi antigen-reactive T cell clones isolated from a patient with Lyme disease.  Journal of Immunology 150: 4125-35, 1993.
  • Jackman, J., Motto, D., Sun, Q., Tanemoto, M., Turck,C.W., Peltz, G.A., Koretzky, G.A., Findell, P.R.  Molecular  cloning of SLP76, a 76 kDa tyrosine phosphoprotein associated with Grb2 in T cells.  J. Biol. Chem. 240:2029-32, 1995.
  • Shanafelt, M-C., Soderberg, C., Allsup, A., Adelman, D., Peltz, G., and Lahesmaa, R. Costimulatory signals can selectively modulate cytokine production by CD4+ T cells.  J. Immunol.  154:1684-90, 1995.
  • Lahesmaa, R., Soderberg, C., Bliska, J., Leirisalo-Repo, M., Luukkainen, R., Steinman, L., and G. Peltz. Pathogen antigen and superantigen-responsive T cells in reactive arthritis. J. Inf. Dis.  172:1290-97, 1995.
  • Begovich, A.B., Klitz, W., Moonsamy, P.V., Van de Water J., Peltz, G., Gershwin, M.E. Genes within the HLA class II region confer both predisposition and resistance to primary biliary cirrhosis. Tissue Antigens 43: 71-7, 1994.
  • Lahesmaa, R, Shanafelt, M.C., Steinman, L., Peltz, G.  Immunopathogenesis of human inflammatory arthritis: lessons from Lyme and reactive arthritis. J. Inf. Dis. 170:978-85, 1994.
  • Lahesmaa, R., Yssel, H., Batsford, S., Luukkainen, R., Möttönen, T., Steinman, L., Peltz, G. Yersinia enterocolitica activates a T helper type 1-like T cell subset in reactive arthritis.  Journal of Immunology 148:3079-85, 1992.
  • Anzola, J., Luft, B.J., Gorgone, Dattwyler, R.J., Soderberg C., Lahesmaa, R., Peltz, G. Borrelia burgdorferi HSP70 homolog: characterization of an immunoreactive stress protein. Infection and Immunity 60:3704-13 1992.
  • Anzola, J., Luft, B.J., Gorgone, G., Peltz, G. Characterization of a Borrelia burgdorferi dnaJ homolog. Infection and Immunity 60:4965-8, 1992.
  • Shanafelt, M.C.,  Anzola, J., Soderberg, C., Yssel, H., Turck, C., and G. Peltz. Epitopes on the outer surface protein A of Borrelia burgodorferi recognized by antibodies and T cells of Lyme arthritis patients.  J. Immunology 146:3985-3992, 1992.
  • Collins, C., Peltz, G.  Immunoreactive epitopes on an expressed recombinant flagellar protein of Borrelia burgdorferi. Infection and Immunity 59:514-20, 1991.
  • Peltz, G. A role for CD4+ T cell subsets producing a selective pattern of lymphokines in the pathogenesis of human chronic inflammatory and allergic diseases. Immunology Reviews 123:23-35, 1991.
  • Shanafelt, M.C., Hindersson, P., Soderberg, C., Mensi, N., Turck, C.W., Webb, D., Yssel, H., Peltz, G.   T cell and antibody reactivity with the Borrelia burgdorferi 60-kDa heat shock protein in Lyme arthritis.  Journal of Immunology 146: 3985-92, 1991.
  • Yssel, H., Shanafelt, M.-C., Soderberg, C., Schneider, P., Anzola, J., and G. Peltz.  B. burgdorferi activates a TH1-like T cell subset in Lyme arthritis.  J. Experimental Medicine 174:593-601, 1991.
  • Yssel, H., Nakamoto, T., Schneider, P., Freitas, V., Collins, C., Webb, D., Mensi, N., Soderberg, C., Peltz, G. Analysis of T lymphocytes cloned from the synovial fluid and blood of a patient with Lyme arthritis. International Immunology 2:1081-9,1990.
  • Mensi, N., Webb, D.R., Turck, C.W., Peltz, G.A.  Characterization of Borrelia burgdorferi proteins reactive with antibodies in synovial fluid of a patient with Lyme arthritis. Infection and Immunity 58:2404-7, 1990.
  • Trounstine, M.L., Peltz, G.A., Yssel, H., Huizinga, T.W., von dem Borne,A.E., Spits, H., Moore, K.W. Reactivity of cloned, expressed human Fc gamma RIII isoforms with monoclonal antibodies which distinguish cell-type-specific and allelic forms of Fc gamma RIII.  International Immunology 2:303-10, 1990.
  •  Peltz, G., Frederick, K., Anderson, C.L., Peterlin-B.M. Characterization of the human monocyte high affinity Fc receptor (hu FcRI). Molecular immunology 25:243-50,1988.
  • Peltz, G., Grundy, H., Lebo, R., Yssel, H., Barsh, G. and K. Moore.  Human Fc RIII: cloning, expression and identification of the chromosomal locus of two Fc receptors for IgG.  Proc. Natl. Acad. Sci. 86:1013‑1017, 1989.
  • Grundy, H.O., Peltz, G., Moore, K.W., Golbus, M.S., Jackson, L.G., Lebo, R.V. The polymorphic Fc gamma receptor II gene maps to human chromosome 1q. Immunogenetics 29:331-9,1989.
  • Peltz, G., Trounstein, M. and K. Moore.  Cloned and expressed human Fc RII mediates anti‑CD3 induced lymphoproliferation.  Journal of Immunology 141:1891‑1896, 1988.
  • Peltz, G.A., Gallis, B., Peterlin, B.M. Monoclonal antibody immunoprecipitation of cell membrane glycoproteins. Analytical Biochemistry 167:239-44, 1987.
  • Peltz, G., Spudich, J.A., Parham, P. Monoclonal antibodies against seven sites on the head and tail of Dictyostelium myosin. The Journal of Cell Biology 100:1016-23,1985.
  • Flicker, P., Peltz, G., Sheetz, M., Parham, P. and J. Spudich.  Site‑specific inhibition of myosin‑mediated motility in vitro by monoclonal antibodies.  The Journal of Cell Biology 100:1024‑1030, 1985.
  • Peltz, G., Kuczmarski, E. and J. Spudich.  Dictyostelium myosin: characterization of chymotryptic subfragments and localization of a heavy chain phosphorylation site.  J. Cell Biol. 89:104‑108, 1981.
  • Livingston, D.C., Brocklehurst, J.R., Cannon, J.F., Leytus, S.P., Wehrly, J.A., Peltz, S.W., Peltz, G.A., Mangel, W.F. Synthesis and characterization of a new fluorogenic active-site titrant of serine proteases. Biochemistry 20:4298-306, 1981.
  • Leytus, S.P., Peltz, G.A., Liu, H.-Y., Cannon, J.F., Peltz, S.W., Livingston, D.C., Brocklehurst, J.R., Mangel, W.F. A quantitative assay for the activation of plasminogen by transformed cells in situ and by urokinase. Biochemistry 20:4307-14, 1981.
  • Mangel, W.F., Livingston, D.C., Brocklehurst, J.R., Cannon, J.F., Leytus, S.P., Peltz, S.W., Peltz, G.A., Liu, H.-Y. A new active-site titrant of serine proteases. Methods in Enzymology 80 Pt C:414-24, 1981.
  • Mangel, W.F., Livingston, D.C., Brocklehurst, J.R., Liu, H.-Y., Peltz, G.A., Cannon, J.F., Leytus, S.P., Wehrly, J.A., Salter, B.L., Mosher, J.L. New assay for the plasminogen activator activity of transformed cells. Cold Spring Harbor Symposia on Quantitative Biology 44(1):669-80, 1980.
  • Liu, H.-Y., Peltz, G.A., Leytus, S.P., Livingston, C., Brocklehurst, J., Mangel, W.F.. Sensitive assay for plasminogen activator of transformed cells. Proc. Natl. Acad. Sci 77:3796-800, 1980.
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